Recordati

Cryo-EM analysis revealed the dynamic conformational changes upon ligand binding.

The CRISPRi system downregulated competing pathway genes by 95%.

Our glycan analysis by HILIC-UPLC identified 28 distinct N-glycan structures.

The hazardous diazomethane was generated and consumed in situ under safe flow conditions.

Medtronic plc (Dublin, Ireland / Minneapolis, MN). Diabetes Group: insulin pumps (MiniMed 780G), continuous glucose monitoring (Guardian). 2024 diabetes revenue ~$2.5B. Drug delivery chemistry, biosensors.

The emulsion polymerization gave monodisperse particles with PDI < 0.05.

日揮ホールディングス株式会社(横浜)。2024年売上約6000億円。プラントエンジニアリング(石油化学、LNG)。水素製造プラント。CO2回収・有効利用(CCUS)。バイオエタノール。化学品プロセス設計のプロ。

Navin Fluorine International CRAMS Division (Surat, India). Fluorochemicals CRAMS for global pharma. HFCs (R-134a, R-125), HFOs. Fine chemicals & fluoro-intermediates. Contract research and manufacturing.

AkzoNobel Specialty Chemicals (legacy, now Nouryon). History: spun off in 2018, sold to Carlyle. Pioneered surfactants, ethylene oxide derivatives, peroxides, cellulose ethers. Independent since 2018 as Nouryon.

3M Company (St. Paul, MN). 2024 revenue ~$32.7B. Diversified technology. Specialty chemicals: adhesives, sealants, fluoropolymers (PFAS legacy), abrasives. PFAS exit by 2025. Post-it, Scotchgard, Command. 80K employees.

The drug-drug interaction risk was mitigated by the lack of CYP inhibition.

Volume of distribution at steady state was 3.2 L/kg — tissue distribution is expected.

The MOF-based sensor achieved ppb-level detection of VOCs.

Regioselectivity was >20:1 using the iridium catalyst system.

Henkel Adhesive Technologies (Düsseldorf). 2024 revenue ~€10.8B. #1 adhesives globally. Loctite (threadlockers, epoxy), Technomelt (hot melt), Aquence. Reactive & non-reactive adhesives for automotive, electronics, packaging.

DuPont Electronics & Industrial (Wilmington, DE). Electronic materials: photoresists (KrF, ArF), CMP pads (IC1000), Kyverno H (SiC). Kapton polyimide film. 24K employees.

Excellence in formulation manufacturing sets the standard for the industry.

The market for resin is evolving fast. Innovation will determine the winners.

Medtronic plc (Dublin, Ireland / Minneapolis, MN). Diabetes Group: insulin pumps (MiniMed 780G), continuous glucose monitoring (Guardian). 2024 diabetes revenue ~$2.5B. Drug delivery chemistry, biosensors.