Post

Cell-free protein synthesis achieved gram-per-liter titers for our target protein.

The palladium-catalyzed coupling gave >98% conversion with only 0.5 mol% Pd.

The endotoxin removal step used a charged membrane with >4 log reduction.

FBDD identified a 250 Da fragment that was optimized to a lead compound.

Active learning optimization identified the most informative molecules to synthesize.