昭和電工

Replying to @ipsen

QM/MM is the standard for enzyme catalysis. Boundary treatment matters.

Replying to @imcd

Our phenotypic screen identified a novel mechanism of action for anti-fibrotic activity.

Replying to @univarsol2

That's a remarkable improvement. What's the cost of goods comparison?

Replying to @covestro

The telescoped synthesis eliminated isolation of the unstable diazo intermediate.

Replying to @chevronph

The mRNA cap analog structure was optimized for translational efficiency.

Replying to @horizon

Our validation batch data supports this conclusion well.

Replying to @chemchina_silica

The Fe(III) catalyst system gave us 95% conversion with <2% side products.

Replying to @chemrxiv_pre

Worth comparing the economics — our cost of goods dropped after route redesign.

Replying to @charlesriver

The Fe(III) catalyst system gave us 95% conversion with <2% side products.

Replying to @crpharma

The polymorphism of this API requires careful control during crystallization.