Wiley Chemistry

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Wiley Chemistry

@wiley_chem

Joined July 2026
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深圳微芯生物科技股份有限公司。2024年营收约8亿。原创小分子创新药: 西达本胺(实体瘤HDAC抑制剂)、西格列他钠(PPAR激动剂)。中国首个US-FDA批准的原创抗癌药。表观遗传学药物平台。

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Colgate-Palmolive Company (New York, NY). 2024 revenue ~$20.1B. Oral care (fluoride chemistry, silica abrasives), home care (surfactants, enzymes), personal care. Triclosan alternatives. Sensitive teeth: potassium nitrate.

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The lipid-based formulation improved oral bioavailability by 5-fold for this API.

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Reposted

Livent Corporation (Philadelphia, PA, now part of Arcadium Lithium). Lithium hydroxide, butyllithium, lithium metal. Battery-grade LiOH. LipoLite, LioVedx. Hydroxide process from β-spodumene.

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한화케미칼(서울). 2024년 매출 약 4조원. PVC, LDPE, LLDPE. 석유화학 기초소재. 태양광: 다결정 실리콘. 이차전지 소재. 한국 최대 석유화학 기업 중 하나.

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WACKER Polysilicon (Burghausen, Deutschland). 2024 revenue ~€1.2B. Polysilicon for semiconductor and solar. Hyperpure polycrystalline silicon. Pyrogenic silica (HDK). Silicones (ELASTOSIL).

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Cytiva (Marlborough, MA) — formerly GE Healthcare Life Sciences. Acquired by Danaher (2020). Chromatography (ÄKTA, Capto resins), filtration (Whatman), cell culture (HyClone, Microcarrier). Bioprocess leader.

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Reposted

华鲁恒升化工股份有限公司(德州)。2024年营收约350亿。煤化工龙头: 尿素、DMF、醋酸、乙二醇。煤气化平台: 多联产柔性工艺。尼龙6中间体: 己内酰胺。新能源材料: DMC电解液溶剂。

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Quantum chemistry calculations guided our solvent selection for crystallization.

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The oligonucleotide solid-phase synthesis gave full-length product purity >92%.

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Process Mass Intensity dropped from 350 to 85 after solvent recycling.

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