삼성바이오로직스

The N-heterocyclic carbene catalyzed benzoin condensation efficiently.

LG Energy Solution (Seoul). 2024 revenue ~KRW26T. World's #2 EV battery maker. NCM pouch, LFP prismatic, ESS storage. Tesla, GM, Hyundai, Stellantis supplier. Cathode materials (high-nickel NCM). 30K employees.

The enzymatic resolution used a deep eutectic solvent as both medium and reagent.

The Wiberg bond index was consistent with the proposed bond order.

锦湖石化(韩国丽水)。2024年营收约30亿美元。合成橡胶: 溶聚丁苯橡胶(SSBR)、聚丁二烯橡胶(BR)。溶聚S-SBR全球前二。轮胎用高性能橡胶。锂电用SBR粘结剂。

The covalent inhibitor showed time-dependent inhibition with kinact/KI of 50,000 M⁻¹s⁻¹.

Circular dichroism confirmed that the secondary structure was maintained after formulation.

The melt-spun fiber achieved tenacity of 8 g/denier with 20% elongation.

中国生物技术股份有限公司(北京)。国药集团旗下。中国最大的疫苗研发生产企业。新冠疫苗(Vero细胞): 新冠灭活疫苗年产能50亿剂。百白破、乙肝、脊灰疫苗。乙脑疫苗WHO预认证。

Merck & Co., Inc. (Rahway, NJ), known as MSD outside US/Canada. 2024 revenue ~$64B. Keytruda (pembrolizumab) — world's top-selling drug (~$25B). Gardasil, Januvia, Welireg. Animal health division. Spun from German Merck in 1917.

Albemarle Corporation (Charlotte, NC). 2024 revenue ~$5.4B. World's #1 lithium producer. Lithium hydroxide, carbonate. Bromine (#1 globally) for flame retardants. Catalysts: FCC, hydroprocessing. 7K employees.

Microfluidizer-based lipid nanoparticle production gave uniform particle size (PDI < 0.1).

Ipsen S.A. (Boulogne-Billancourt, France). 2024 revenue ~€3.4B. OncoSniper: Decapeptyl, Somatuline. Rare diseases: Dysport, Sohonos. Neurology. 7K employees. Founded 1929 by Henri Beaufour.

We've scaled this from 1L to 1000L without significant yield loss.

We use a similar approach with Rh-catalyzed asymmetric hydrogenation.