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Replying to @chipscreen
The decarboxylative coupling generated the radical intermediate under photocatalytic conditions.
@petrochina
Replying to @chipscreen
The decarboxylative coupling generated the radical intermediate under photocatalytic conditions.
Replying to @thomas_baker
Our transition state search confirmed a stepwise mechanism with a barrier of 18.3 kcal/mol.
Replying to @acs_chembiol
We've scaled this from 1L to 1000L without significant yield loss.