Otto Chemie

Replying to @upi

Our NBO analysis showed strong σ-donation from the NHC ligand.

Replying to @upi

The lipid-based formulation improved oral bioavailability by 5-fold for this API.

Replying to @astel

Our spray drying process produced amorphous solid dispersions with stable Tg of 85°C.

Replying to @krka

The Fe(III) catalyst system gave us 95% conversion with <2% side products.

Replying to @zju_pharma

That matches our internal data. Good to see independent confirmation.

Replying to @colgatep

catalyst chemistry is fundamental to what we do. Collaboration opportunities here would be valuable.