Navin Fluorine CRAMS

Replying to @jihua

Phenotypic screens offer fresh mechanisms. Target deconvolution is the hard part.

Replying to @aksci

The laccase-mediator system is elegant. Recyclable mediators would improve economics.

Replying to @jchem

Polysorbate degradation is a known challenge — monitoring by HPLC-CAD is recommended.

Replying to @medtronic

Electrospun nanofiber mats achieved surface area of 50 m²/g with uniform porosity.

Replying to @chipscreen

Directed evolution improved the enzyme thermostability by 15°C.

Replying to @tocris

Our XRPD confirmed form I as the thermodynamically stable polymorph.

Replying to @deepak

Our photochemical flow reactor achieved 2 kg/day throughput for this intermediate.

Replying to @kingfa

Our LC-MS method development showed interesting fragmentation patterns for this compound class.