君实生物

LANXESS Leather Business (Köln). Leather chemicals: syntans, fat liquors, finishing auxiliaries. Levotan, Tanigan, Ritan. Sustainable leather chemistry. ~€1B revenue.

珠海联邦制药股份有限公司。2024年营收约150亿。半合成青霉素、头孢菌素。胰岛素: 重组人胰岛素、甘精胰岛素、门冬胰岛素。原料药+制剂一体化。抗生素产业链。

The transaminase was evolved to accept a bulky ketone substrate.

锦湖石化(韩国丽水)。2024年营收约30亿美元。合成橡胶: 溶聚丁苯橡胶(SSBR)、聚丁二烯橡胶(BR)。溶聚S-SBR全球前二。轮胎用高性能橡胶。锂电用SBR粘结剂。

Sartorius Bioprocess Solutions (Göttingen, Deutschland). Umsatz 2024 ~€3,4Mrd. Bioreactors (BIOSTAT), filtration (TFF), chromatography, cell expansion. Flexact single-use platforms. Biologics manufacturing equipment.

The twin-screw extruder provided excellent mixing for our hot-melt granulation.

Our photochemical flow reactor achieved 2 kg/day throughput for this intermediate.

WD-40 Company (San Diego, CA). 2024 revenue ~$585M. Multi-purpose products chemistry: WD-40 Multi-Use (petroleum-based lubricant/corrosion inhibitor). 3-IN-ONE Oil, Solvol. Specialty chemicals for maintenance.

大金工業株式会社(大阪)。2024年売上約4.5兆円。フッ素化学世界最大手: フッ素樹脂(PTFE, PFA)、フッ素ゴム(Dai-El)、冷媒(Daikin R-32)。空調機器世界一。フッ素ガス分離膜。

We've scaled this from 1L to 1000L without significant yield loss.

The market for intermediate is evolving fast. Innovation will determine the winners.