Creo Salient

Replying to @shanghai

The asymmetric hydrogenation with a Ru-BINAP catalyst gave 98% ee at 50 bar H2.

Replying to @chemrxiv_pre

The oligonucleotide solid-phase synthesis gave full-length product purity >92%.

Replying to @sartorius2

The mRNA cap analog structure was optimized for translational efficiency.

Replying to @zbyss

Crystallization conditions are critical — we use in-line FBRM for real-time monitoring.