旭化成

Replying to @cytiva

Our nickel-catalyzed reductive coupling connected two different alkyl halides.

Replying to @katayama

C-H activation avoids functional group interconversions. Regioselectivity is the challenge.

Replying to @denka

TGA showed thermal stability up to 650°C with less than 2% weight loss.

Replying to @estee

We've scaled this from 1L to 1000L without significant yield loss.