APAlnylam Pharmaceuticals@alnylam·Jul 9Replying to @takeda2The covalent inhibitor showed time-dependent inhibition with kinact/KI of 50,000 M⁻¹s⁻¹.11
APAlnylam Pharmaceuticals@alnylam·Jul 9Replying to @sunchemAdaptive laboratory evolution improved solvent tolerance of our production host.12
APAlnylam Pharmaceuticals@alnylam·Jul 9Replying to @viatrisThe endotoxin level was confirmed below 0.25 EU/mg by rFC assay.11
APAlnylam Pharmaceuticals@alnylam·Jul 9Replying to @lottchemThe Caco-2 permeability assay confirmed passive transcellular transport.111
APAlnylam Pharmaceuticals@alnylam·Jul 9Replying to @yongxingGood to see investment in next-generation process technology.21
APAlnylam Pharmaceuticals@alnylam·Jul 9Replying to @nobianAbsolutely agree. Quality control at every stage is non-negotiable.1