依托米脂 更新时间：2023-02-17 09:49:57 常用名 依托咪酯 CAS号 33125-97-2 价钱 ￥需询单/1kg 纯度 99.0% 备货期 需询单 库存 现货 产物详情（用途，包装等） 用途： Etomidate(R-16659) is a GABAA receptors agonist, which is a short acting intravenous anaesthetic agent used for the induction of general anaesthesia.Target: GABA ReceptorEtomidate is a potent inhibitor of the adrenal response to surgery. The absence of clinical consequences associated with the blunted response suggests that a major increase in adrenal hormone production may not be necessary during surgery [1]. Etomidate is an intravenous induction agent that is associated with hemodynamic stability during intubation. The agent is therefore attractive for use in critically ill patients who have a high risk of hemodynamic instability during this procedure [2]. Etomidate use was not associated with all cause 28-day mortality or hospital mortality but was associated with significantly higher ICU mortality (91% vs. 64% for etomidate and controls groups, respectively; p = 0.02). Etomidate patients who received subsequent doses of hydrocortisone required lower doses of vasopressors and had more vasopressor-free days but no improvement in mortality [3].Clinical indications: FDA Approved Date: 1983Toxicity: Undesirable side effects of etomidate that may limit its use include pain on injection, myoclonus and adrenocortical suppression lasting 4-6 hours following an induction dose. 物理化学性子： CAS号：33125-97-2 常用中文名：依托咪酯 常用英文名：Etomidate 分子式：C14H16N2O2 分子量：244.289 密度：1.1±0.1 g/cm3 沸点：391.5±17.0 °C at 760 mmHg 熔点：72-74ºC 闪点：190.6±20.9 °C 储存条件：2-8°C 供应商信息 河北方乾新质料科技有限公司 认证状态： 未认证供应商 电话： 18034395858 地址： 联邦名都三期 区域： 河北省 石家庄市 桥西区 联系人： 18034395858 联系人电话： 18034395858 邮件： lris@rilonchem.com 年商业额： 100000000 河北方乾新质料科技有限公司是一家专业生产医药中央体的企业，公司拥有自力的研发团队，可以开发和定制任何医药质料，拥有领先的手艺团队和先进的生产装备，价钱低、质量高、服务一流，

依托咪酯 更新时间：2021-09-28 10:44:01 常用名 依托咪酯 CAS号 33125-97-2 价钱 ￥需询单/1kg 纯度 99.0% 备货期 需询单 库存 询单 产物详情（用途，包装等） 用途： Etomidate(R-16659) is a GABAA receptors agonist, which is a short acting intravenous anaesthetic agent used for the induction of general anaesthesia.Target: GABA ReceptorEtomidate is a potent inhibitor of the adrenal response to surgery. The absence of clinical consequences associated with the blunted response suggests that a major increase in adrenal hormone production may not be necessary during surgery [1]. Etomidate is an intravenous induction agent that is associated with hemodynamic stability during intubation. The agent is therefore attractive for use in critically ill patients who have a high risk of hemodynamic instability during this procedure [2]. Etomidate use was not associated with all cause 28-day mortality or hospital mortality but was associated with significantly higher ICU mortality (91% vs. 64% for etomidate and controls groups, respectively; p = 0.02). Etomidate patients who received subsequent doses of hydrocortisone required lower doses of vasopressors and had more vasopressor-free days but no improvement in mortality [3].Clinical indications: FDA Approved Date: 1983Toxicity: Undesirable side effects of etomidate that may limit its use include pain on injection, myoclonus and adrenocortical suppression lasting 4-6 hours following an induction dose. 物理化学性子： CAS号：33125-97-2 常用中文名：依托咪酯 常用英文名：Etomidate 分子式：C14H16N2O2 分子量：244.289 密度：1.1±0.1 g/cm3 沸点：391.5±17.0 °C at 760 mmHg 熔点：72-74ºC 闪点：190.6±20.9 °C 储存条件：2-8°C 供应商信息 北京睿悦生物医药科技有限公司 认证状态： 未认证供应商 电话： 010-56541008 地址： 北京丰台区科技园航丰路8号1号楼523 区域： 北京市 北京市 丰台区 联系人： 郑慧贤 联系人电话： 15901075650 邮件： 1078484058@qq.com

CAS号: 33125-97-2 英文名称: Etomidate 英文同义词: R16659;R-1665;AMIDATE;Etomidat;PROPISCIN;ETOMIDATE;RADENARCON;D-ETOMIDATE;HYPNOMIDATE;Etomidate> 中文名称: 依托咪酯 中文同义词: 嘧羟酯;乙咪酯;乙苄咪唑;依托咪酯;甲苄咪酯;依托咪酯杂质;依托咪酯 1G;依托咪酯氧化杂质;依托咪酯(标准品);依托咪酯 EP标准品 分子式: C14H16N2O2 分子量: 244.29 熔点 : 72-74°C 比旋光度 : D20 +66° (c = 1 in ethanol) 沸点 : 160-162 °C(Press: 1 Torr) 密度 : 1.11±0.1 g/cm3(Predicted) 储存条件 : 2-8°C 溶解度 : DMSO: >10 mg/mL 形态: powder 酸度系数(pKa): pKa 4.24(H2O t=25.0) (Uncertain) 颜色: white Merck : 14,3881 CAS 数据库: 33125-97-2(CAS DataBase Reference) NIST化学物质信息: Etomidate(33125-97-2) 危险品标志 : Xn 危险类别码 : 22 安全说明 : 36 危险品运输编号 : UN 3077 9 / PGIII WGK Germany : 3 RTECS号: NI4021500 HazardClass : 9 PackingGroup : III 海关编码 : 29332900 毒性: LD50 in mice, rats (mg/kg): 29.5, 14.8-24.3 i.v. (Janssen)