CAS 1217457-86-7

CAS 1217457-86-7

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CAS号: 1217457-86-7 英文名称: GGTI 298 trifluoroacetate salt hydrate 英文同义词: GGTI-298 TFA;GGTI 298 TFA salt;GGTI298 Trifluoroacetate;WALKWJPZELDSKT-UFABNHQSSA-N;GGTI 298 trifluoroacetate salt hydrate;GGTI 298 TFA SALT;GGTI 298 (TRIFLUOROACETATE SALT);N-[[4-(2-(R)-Amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt hydrate 中文名称: GGTI-298 TFA 中文同义词: GGTASE I抑制剂(GGTI298 TRIFLUOROACETATE) 分子式: C29H34F3N3O5S 分子量: 593.6575696 熔点 : 99.5-100°C 储存条件 : ?20°C 溶解度 : DMSO: >20mg/mL 形态: film &_& lyophilized 颜色: colorless 危险品标志 : Xi 危险类别码 : 36/37/38 安全说明 : 26-36 WGK Germany : 3

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GGTI-298 TFA 更新时间:2020-12-18 22:54:27 采购访问:1次 常用名 GGTI298三氟乙酸盐 CAS号 1217457-86-7 价格 $需询单/100mg $需询单/250mg $需询单/500mg 纯度 98.0% 备货期 3天 库存 现货 产品网页 www.dcchemicals.com/product_show-GGTI-298_TFA.html 产品详情(用途,包装等) GGTI-298 is a potent geranylgeranyltransferase-I (GGTase-I) inhibitor with potential antitumor actrivity. GGTI-298 disrupts MAP kinase activation and G(1)-S transition in Ki-Ras-overexpressing transformed adrenocortical cells. GGTI-298 induces hypophosphorylation of retinoblastoma and partner switching of cyclin-dependent kinase inhibitors. A potential mechanism for GGTI-298 antitumor activity. GGTI-298 arrests human tumor cells in G0/G1 and induces p21(WAF1/CIP1/SDI1) in a p53-independent manner. GGTI-298 induces G0-G1 block and apoptosis whereas FTI-277 causes G2-M enrichment in A549 cells. 供应商信息 DC Chemicals Limited 认证状态: 已认证供应商 商品数: 20124件 电话: 58447131 地址: 浦东新区金豫路100号 地区: 上海市 上海市 浦东新区 联系人: Tony Cao 联系人电话: 862158447131 邮件: [email protected] 网址: www.dcchemicals.com 年贸易额: >1000万 D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use. D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan. We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers. Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.