氟他胺
更新时间：2021-12-20 09:27:01
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常用名 |
氟他胺 |
CAS号 |
13311-84-7 |
| 价钱 |
￥1000.0/1kg |
纯度 |
99.0% |
| 备货期 |
1天 |
库存 |
询单 |
产物详情（用途，包装等）
用途：
Flutamide is an antiandrogen drug, with its active metablolite binding at androgen receptor with Ki values of 55 nM, and primarily used to treat prostate cancer.Target: androgen receptor in vitro: Flutamide (Eulexin) is an antiandrogen drug. Flutamide-OH, the active metabolite of flutamide, directly binds at rat anterior pituitary androgen receptor with Ki values of 55 nM [1]. lutamide does not affect the proliferation of an androgen-sensitive clone of the mouse mammary carcinoma Shionogi SC-l 15 cells in culture, shows only antiandrogenic effect, but not androgenic effect [2]. Flutamide provides treatment for prostate cancer when used along with leuprolide [3].in vivo: Flutamide causes a markedly reduction in rat ventral prostate weight from 319 mg to 245 mg. A combination of flutamide and LHRH agonist induces an additive effect with a decrease in prostate weight to 101 mg, and an marked drop in prostatic ODC activity [4].
物理化学性子：
CAS号：13311-84-7
常用中文名：氟他胺
常用英文名：Flutamide
分子式：C11H11F3N2O3
分子量：276.212
密度：1.4±0.1 g/cm3
沸点：400.3±45.0 °C at 760 mmHg
熔点：112 °C
闪点：195.9±28.7 °C
储存条件：Store at RT |
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