Onalespib lactate
更新时间:2020-12-18 22:54:27
采购访问:1次
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常用名 |
Onalespib lactate |
CAS号 |
1019889-35-0 |
价格 |
$需询单/100mg $需询单/250mg $需询单/500mg |
纯度 |
98.0% |
备货期 |
3天 |
库存 |
现货 |
产品网页 |
http://www.dcchemicals.com/product_show-Onalespib_lactate.html |
产品详情(用途,包装等) Onalespib lactate, also known as ATI-13387A, is a second-generation, potent and selective HSP90 Inhibitor. Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells. Inhibition of HSP90 by AT13387 delays the emergence of resistance to BRAF inhibitors and overcomes resistance to dual BRAF and MEK inhibition in melanoma models. AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation. AT13387, displays a long duration of action in vitro and in vivo in non-small cell lung cancer. |
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