p38 MAP Kinase Inhibitor IV
更新时间:2020-12-18 22:54:27
采购访问:1次
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常用名 |
2,2’-磺酰基双(3,4,6-三氯苯酚) |
CAS号 |
1638-41-1 |
价格 |
$需询单/100mg $需询单/250mg $需询单/500mg |
纯度 |
98.0% |
备货期 |
3天 |
库存 |
现货 |
产品网页 |
http://www.dcchemicals.com/product_show-p38_MAP_Kinase_Inhibitor_IV.html |
产品详情(用途,包装等) p38 MAP Kinase Inhibitor IV is an ATP-competitive inhibitor of p38α/β MAPK with IC50 values of 130 nM for p38α and 550 nM for p38β. It is much less active with ≤23% inhibition at 1 μM against p38γ/σ, ERK1/2, and JNK1/2/3. Shown to be more effective than SB 203580 in inhibiting LPS-induced IL-1β release from hPBMC (100% vs. 50% inhibition with 100 μM inhibitor). A recent study showed that p38 MAP Kinase Inhibitor IV could consistently and significantly enhance reprogramming and iPS cell generation from somatic cells. |
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