SDX102
更新时间:2020-12-18 22:54:27
采购访问:1次
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常用名 |
丙氨菌素 |
CAS号 |
5854-93-3 |
价格 |
$需询单/100mg $需询单/250mg $需询单/500mg |
纯度 |
98.0% |
备货期 |
3天 |
库存 |
现货 |
产品网页 |
http://www.dcchemicals.com/product_show-SDX102.html |
产品详情(用途,包装等) Alanosine, also known as L-alanosine, is an amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities. L-alanosine inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate, an intermediate in purine metabolism. L-alanosine-induced disruption of de novo purine biosynthesis is potentiated by methylthioadenosine phosphorylase (MTAP) deficiency. The clinical use of this agent may be limited by its toxicity profile. MTAP is a key enzyme in the adenine and methionine salvage pathways. |
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