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供应信息 2021-1-6 22:25 142
IP: 美国

PD-85639

更新时间:2020-12-18 22:54:27 采购访问:1次

常用名 PD-85639 CAS号 149838-21-1
价格 $需询单/100mg $需询单/250mg $需询单/500mg 纯度 98.0%
备货期 3天 库存 现货
产品网页 http://www.dcchemicals.com/product_show-PD-85639.html
 产品详情(用途,包装等)
PD-85639 is a voltage-gated sodium (Na+) channel blocker (75% in 10 min & >95% in 25 min blockage of Na+ current by 25 μM PD85,639; whole-cell patch clamp using primary rat brain neurons) that is shown to target rat brain Nav1.2 with simultaneous high- and low-affinity modes of binding (EC50 = 56 nM/40% & 20 μM/60% at pH 9.0, 5 nM/28% & 3 μM/72% at pH 7.4, against 2 nM [3H]-PD85,639 for binding rat brain synaptosomes; EC50 = 17 nM/39% & 10 μM/61% using at pH 9.0 using rat brain synaptosome membranes) and a fast kinetic (t1/2 = 1.2 at 4°C, <0.5 min at 25°C), competitive against the local anesthetic Na+ channel blockers tetracaine, bupivacaine, and mepivacaine, as well as Na+ channel activators veratridine and batrachotoxin (K1 = 0.26 μM against 5 nM [3H]-BTX for binding rat neocrotical membranes).

供应商信息

DC Chemicals Limited

认证状态:已认证供应商
商品数:20124件
电话:58447131
地址:浦东新区金豫路100号
地区: 上海市 上海市 浦东新区
联系人:Tony Cao
联系人电话:862158447131
邮件:sales@dcchemicals.com
网址:http://www.dcchemicals.com
年贸易额:>1000万
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.



D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.

We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.





Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
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