Hydroxy desmethyl Bosentan
更新时间:2020-12-18 22:54:27
采购访问:1次
|
常用名 |
Hydroxy desmethyl Bosentan |
CAS号 |
253688-62-9 |
价格 |
|
纯度 |
98.0% |
备货期 |
3天 |
库存 |
现货 |
产品网页 |
http://www.dcchemicals.com/product_show-Hydroxy-desmethyl-Bosentan.html |
产品详情(用途,包装等) Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver. Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Bosentan can be used in treatment of pulmonary arterial hypertension. |
|