D-α-Hydroxyglutaric acid
更新时间:2020-12-18 22:54:27
采购访问:1次
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常用名 |
D-α-Hydroxyglutaric acid |
CAS号 |
13095-47-1 |
价格 |
$需询单/250mg $需询单/100mg $需询单/1g |
纯度 |
98.0% |
备货期 |
3天 |
库存 |
现货 |
产品网页 |
http://www.dcchemicals.com/product_show-D-alpha-Hydroxyglutaric_acid.html |
产品详情(用途,包装等) D-α-Hydroxyglutaric acid ((R)-2-Hydroxypentanedioic acid) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. D-α-Hydroxyglutaric acid increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling. |
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