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供应信息 2021-1-6 21:02 112
IP: 日本

GLL398

更新时间:2020-12-18 22:54:27 采购访问:1次

常用名 GLL398 CAS号 2077980-83-5
价格 $需询单/100mg $需询单/250mg $需询单/500mg 纯度 98.0%
备货期 3天 库存 现货
产品网页 http://www.dcchemicals.com/product_show-GLL398.html
 产品详情(用途,包装等)
GLL398 is an Oral Selective Estrogen Receptor Downregulator. GLL398 strongly binds to ERα in a fluorescence resonance energy transfer binding assay (IC50 =1.14 nM) and potently degrades ERα in MCF-7 breast cancer cells (IC50 = 0.21 μM). Most importantly, the introduction of the boronic acid group confers superior oral bioavailability of GLL398 (AUC = 36.9 μg·h/mL) in rats as compared to GW7604 (AUC = 3.35 μg·h/mL). The strikingly favorable pharmacokinetic property of GLL398 makes it a promising oral SERD suitable for clinical evaluation.

供应商信息

DC Chemicals Limited

认证状态:已认证供应商
商品数:20124件
电话:58447131
地址:浦东新区金豫路100号
地区: 上海市 上海市 浦东新区
联系人:Tony Cao
联系人电话:862158447131
邮件:sales@dcchemicals.com
网址:http://www.dcchemicals.com
年贸易额:>1000万
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.



D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.

We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.





Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
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