Sorbinil
更新时间:2020-12-18 22:54:27
采购访问:1次
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常用名 |
Sorbinil |
CAS号 |
68367-52-2 |
价格 |
$需询单/100mg $需询单/250mg $需询单/500mg |
纯度 |
98.0% |
备货期 |
3天 |
库存 |
现货 |
产品网页 |
http://www.dcchemicals.com/product_show-Sorbinil.html |
产品详情(用途,包装等) Sorbinil, also known as CP-45634, is an aldose reductase inhibitor potentially for the treatment of diabetes. Aldose reductase is an enzyme present in lens and brain that gets rid of excess glucose by converting it to sorbitol. Sorbitol accumulation can lead to the development of cataracts in the lens and neuropathy in peripheral nerves. Sorbinil has been shown to inhibit aldose reductase in human brain and placenta and calf and rat lens. Sorbinil reduced sorbitol accummulation in rat lens and sciatic nerve of diabetic rats orally administered 0.25mg/kg sorbinil. |
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