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  • Posted @SELL
  • ONC-201 Dihydrochloride,1638178-82-1,DC Chemicals Limited

供应信息 2021-1-6 20:24 387
IP: 美国

ONC-201 Dihydrochloride

更新时间:2020-12-18 22:54:27 采购访问:1次

常用名 ONC-201 DIHYDROCHLORIDE CAS号 1638178-82-1
价格 $需询单/100mg $需询单/250mg $需询单/500mg 纯度 98.0%
备货期 3天 库存 现货
产品网页 http://www.dcchemicals.com/product_show-ONC-201_Dihydrochloride.html
 产品详情(用途,包装等)
ONC-201, also known as TIC10 and imipridone, is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier. TIC10 induces a sustained up-regulation of TRAIL in tumors and normal cells that may contribute to the demonstrable antitumor activity of TIC10. TIC10 inactivates kinases Akt and extracellular signal-regulated kinase (ERK), leading to the translocation of Foxo3a into the nucleus, where it binds to the TRAIL promoter to up-regulate gene transcription. TIC10 is an efficacious antitumor therapeutic agent that acts on tumor cells and their microenvironment to enhance the concentrations of the endogenous tumor suppressor TRAIL.

供应商信息

DC Chemicals Limited

认证状态:已认证供应商
商品数:20124件
电话:58447131
地址:浦东新区金豫路100号
地区: 上海市 上海市 浦东新区
联系人:Tony Cao
联系人电话:862158447131
邮件:sales@dcchemicals.com
网址:http://www.dcchemicals.com
年贸易额:>1000万
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.



D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.

We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.





Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
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