NMS-E973
更新时间:2020-12-18 22:54:27
采购访问:1次
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常用名 |
5-[2,4-二羟基-6-(4-硝基苯氧基)苯基]-N-(1-甲基-4-哌啶基)-3-异恶唑甲酰胺 |
CAS号 |
1253584-84-7 |
价格 |
$需询单/100mg $需询单/250mg $需询单/500mg |
纯度 |
98.0% |
备货期 |
3天 |
库存 |
现货 |
产品网页 |
http://www.dcchemicals.com/product_show-NMS-E973.html |
产品详情(用途,包装等) NMS-E973 is a novel, selective and potent inhibitor of heat shock protein 90 (Hsp90). NMS-E973 displays significant efficacy in a human ovarian A2780 xenograft tumor model, with a mechanism of action confirmed in vivo by typical modulation of known Hsp90 client proteins, and with a favorable pharmacokinetic and safety profile. The efficacy profile of NMS-E973 suggests a potential for development in different clinical settings, including tumors that have become resistant to molecular targeted agents, particularly in cases of tumors which reside beyond the blood-brain barrier (BBB). |
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