Lometrexol hydrate
更新时间:2020-12-18 22:54:27
采购访问:1次
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常用名 |
Lometrexol hydrate |
CAS号 |
1435784-14-7 |
价格 |
$需询单/250mg $需询单/100mg $需询单/1g |
纯度 |
98.0% |
备货期 |
3天 |
库存 |
现货 |
产品网页 |
http://www.dcchemicals.com/product_show-Lometrexol_hydrate.html |
产品详情(用途,包装等) Lometrexol hydrate (DDATHF hydrate), an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol hydrate can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol hydrate has anticancer activity. Lometrexol hydrate also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor. |
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