6(5H)-Phenanthridinone,1015-89-0,DC Chemicals Limited

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6(5H)-Phenanthridinone

更新时间：2020-12-18 22:54:27 采购访问：1次

常用名	6(5H)-5-氮杂菲酮	CAS号	1015-89-0
价格	$需询单/100mg $需询单/250mg $需询单/500mg	纯度	98.0%
备货期	3天	库存	现货
产品网页	http://www.dcchemicals.com/product_show-65H-Phenanthridinone.html

产品详情（用途，包装等） 6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2. It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells. 6(5H)-Phenanthridinone reduces NF-κB-induced transcription of the genes encoding TNF-α, IL-2, and IFN-γ in rat lymphocytes. In vivo, 6(5H)-phenanthridinone reduces spinal cord expression of inducible nitric oxide synthase (iNOS), IL-1β, TNF-α, IL-2, and IFN-γ and reduces disease score in a rat model of experimental autoimmune encephalomyelitis (EAE). It also decreases serum levels of lactate dehydrogenase as well as hepatic lipid peroxidation, oxidative DNA damage, and PARP levels.

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6(5H)-Phenanthridinone,1015-89-0,DC Chemicals Limited

6(5H)-Phenanthridinone,1015-89-0,DC Chemicals Limited

6(5H)-Phenanthridinone

DC Chemicals Limited

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