8-羟基喹啉-5-羧酸
更新时间：2020-11-20 16:59:38
采购访问：1次
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常用名 |
5-羰基-8-羟基喹啉 |
CAS号 |
5852-78-8 |
| 价格 |
￥需询单/1g |
纯度 |
98.0% |
| 备货期 |
需询单 |
库存 |
询单 |
产品详情（用途，包装等）
用途：
IOX1 is the most potent broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases; IC50 for KDM4A/KDM3A is 0.6/0.1 uM.IC50 value: 0.6/0.1 uM(KDM4A/KDM3A) [1]Target: JmjC KDMs inhibitorIOX1 is the most potent against a representative panel of 2OG oxygenases, including non-JmjC 2OG oxygenases, with an in vitro IC50 value in the micromolar range. However, its efficacy in cells is about a hundred-fold lower (HeLa cells, KDM4A, IC50 = 86uM), possibly due to low cell permeability resulting from itspolar C-5 carboxyl group.
物理化学性质：
CAS号：5852-78-8
常用中文名：5-羰基-8-羟基喹啉
常用英文名：5-Carboxy-8-hydroxyquinoline
分子式：C10H7NO3
分子量：189.167
密度：1.5±0.1 g/cm3
沸点：464.5±30.0 °C at 760 mmHg
熔点：N/A
闪点：234.7±24.6 °C
储存条件：2-8°C |
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