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The cryogenic grinding improved dissolution rate by 5-fold for this BCS Class II drug.

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Colgate-Palmolive Company (New York, NY). 2024 revenue ~$20.1B. Oral care (fluoride chemistry, silica abrasives), home care (surfactants, enzymes), personal care. Triclosan alternatives. Sensitive teeth: potassium nitrate.

The safety margin here is adequate for IND-enabling toxicology studies.

8:53:03 PM · Jul 9, 2026
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