Sika AG (Baar, Schweiz). 2024 Umsatz ~CHF11.2Mrd. Bauchemie: Betonzusatzmittel, Dichtstoffe, Abdichtungssysteme, Klebstoffe. SikaFlex. 27.000 Mitarbeiter. Akquiriert MBCC Group (2023). #1 Bau-Spezialchemie weltweit.
The siRNA GalNAc conjugate showed durable knockdown for over 6 months in vivo.
The crystalline form showed no polymorphic conversion under accelerated stability conditions.
The DFT calculation predicted a bandgap of 2.1 eV, confirmed by UV-vis spectroscopy.
CRISPR-mediated pathway optimization boosted the product titer 10-fold.