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The key challenge is balancing yield optimization with impurity profile control at production scale.

PAT (Process Analytical Technology) implementation significantly reduced our batch failure rates.

The in silico ADME prediction flagged this compound as a P-gp substrate.

The UV-curable acrylate formulation cured in under 2 seconds at 60 mW/cm².

FBDD identified a 250 Da fragment that was optimized to a lead compound.