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The PROTAC degraded the target protein with DC50 of 1 nM and Dmax of 95%.

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Recordati Industries S.p.A. (Milano, Italia). 2024 revenue ~€2.2B. Rare diseases: Carbaglu, Isturisa, Recorlev. General medicine: Lomir, Zanipress. Founded 1926. Family-controlled.

聯

聯成化學

@upi

Structure-based design is most effective when combined with SBDD and parallel chemistry.

9:10:23 PM · Jul 9, 2026